ERYTHROMYCIN LACTOBIONATE PACKAGE INSERT PDF

Erythromycin Lactobionate 1g Powder for Solution for Infusion – Summary of Product Characteristics (SmPC) by ADVANZ Pharma. Erythromycin Lactobionate I.V. is a sterile presentation of erythromycin. It is not When administering the product by intermittent infusion do not use solution strengths greater than . includes any possible side effects not listed in this leaflet. Intravenous infusion of mg of erythromycin lactobionate at a constant rate physiologically concentrated or in situations where high dosage of drug can be.

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J01FA01 Erythromycin exerts its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. Erythromycin Lactobionate 1g Powder for Solution for Infusion. Blood and lymphatic system disorders: Always consult your healthcare provider to ensure the information displayed on this packge applies to your personal circumstances.

Erythromycin Lactobionate – I.V. Information –

Elevated cisapride levels have been reported in patients receiving erythromycin and cisapride concomitantly. GranulesErycSign Up Log In Cancel. Hypotension, bradyarrhythmias and lactic acidosis have been observed in patients receiving concurrent verapamil, a calcium channel blocker. Similar effects have been observed with concomitant administration of pimozide and clarithromycin, another macrolide antibiotic.

Continuous infusion of this medicine is preferred due to the slower infusion rate and lower concentration of erythromycin; however, intermittent infusion at intervals not greater than every six hours is also effective.

Erythromycin Lactobionate 1g Powder for Solution for Infusion

Appropriate monitoring should be undertaken and dosage should be adjusted as necessary. Newborn infant birth to 1 month: Marketing authorisation holder 8.

As a result of this plasma levels of active steroid may decrease. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: You may also report side effects at http: You must check to make sure that it is safe for you to take Erythromycin Lactobionate – I. This is not a list of all drugs or health problems that interact with Erythromycin Lactobionate – I.

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By continuing to browse the site you are agreeing to our policy on the use of cookies. There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in infants following erythromycin therapy.

Parents should be informed to contact their physician if vomiting or irritability with feeding occurs. Erythromycin exerts its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections: Reporting suspected adverse reactions after authorisation of the medicinal product is important.

This medicine must be administered by continuous or intermittent intravenous infusion only. Investigations Increased liver enzyme values. Cholestatic hepatitis, jaundice, hepatic dysfunction, hepatomegaly, hepatic failure, hepatocellular hepatitis see section 4.

Call your doctor for medical advice about side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:. Erythromycin has been reported to decrease the clearance of zopiclone and thus may increase the pharmacodynamic effects of this drug.

The majority of strains of Haemophilus influenzae are susceptible to the concentrations reached after ordinary doses. Side effects in more detail. Patients receiving erythromycin concurrently with drugs which can cause prolongation of the QT interval should be carefully monitored.

To view the changes to a medicine you must innsert up and log in. As with other macrolides, rare serious allergic reactions, including acute generalised exanthematous pustulosis AGEP have been reported. If an allergic reaction occurs, the drug should be discontinued and appropriate therapy should be instituted. For Intermittent Infusion lacotbionate 1 gram dose: Lactobionatf for Android and iOS devices.

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Gram positive bacteria – Listeria monocytogenes, Corynebacterium diphtheriae as an adjunct to antitoxinStaphylococci spp, Streptococci spp including Enterococci. This may result in QTc prolongation and cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation and torsades de pointes.

Medically reviewed on Sep 5, Upper Respiratory Tract infections: Benzyl alcohol has been reported to be associated with a fatal ‘Gasping Syndrome’ in premature infants.

Erythromycin Lactobionate – I.V.

Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.

This may lead to sub-therapeutic levels of erythromycin and a decreased effect. Erythromycin is contraindicated in patients taking simvastatin, tolterodine, mizolastine, amisulpride, astemizole, terfenadine, domperidone, cisapride erythromcin pimozide. The same applies for streptomycin, tetracyclines and colistin. This medicine is indicated in severe and immunocompromised cases of infections caused by sensitive organisms where high blood levels are required at the earliest opportunity or when the oral route is compromised.

Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections:. Bronchitis ciprofloxacinamoxicillindoxycyclineazithromycinAugmentinMore Bolus injection IV push is an unacceptable route of administration.

Continue typing to refine. Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen. If you think there has been an overdose, call your poison inxert center or get medical care right away.